Periodontitis is a severe gum infection that damages the soft tissue and bone supporting the teeth, potentially leading to tooth loss if untreated.
Periodontitis is a severe gum infection that damages the soft tissue and bone supporting the teeth, potentially leading to tooth loss if untreated. It develops from untreated gingivitis, where plaque buildup triggers inflammation. As the disease progresses, deep pockets form between the teeth and gums, harboring harmful bacteria that accelerate tissue destruction. Common symptoms include swollen, bleeding gums, bad breath, and loosening of teeth. Risk factors include poor oral hygiene, smoking, diabetes, and genetic predisposition. Periodontitis is one of the leading causes of tooth loss worldwide, affecting millions. Effective management involves professional dental care, improved oral hygiene, and lifestyle changes to prevent further progression and restore gum health.
The Systems Architecture of Periodontitis is published as a web based tool open to public . Click below to interact with the Systems Architecture
A peer-reviewed publication resulting from the Oral Health Research Initiative was published in 2023 in the Journal of American Dental Association. Download the paper below.
In this phase, the Oral Health initiative will conduct in silico modeling to identify and test the efficacy of natural compounds against the Oral Health diseases such as Periodontitis, tooth loss and dental caries
In this phase, combination screening will be performed to identify potential ingredient/compounds that target the biological process implicated in periodontitis pathogenesis. This phase is yet to begin
The Open Science Institute® through its Oral Health Initiative is moving towards getting patents for a revolutionary molecule that effectively combats periodontal disease, contributing breakthrough real solutions to society worldwide.
The Oral Health Initiative plans to discover, develop, license and manufacture proprietary nutraceuticals to support treatment of Periodontitis. Support our mission to bring this innovation to those who need it most. Please support this phase by donating to the Oral Health Initiative
