International Center
for Integrative Systems.

The Power of Systems Thinking

Dr. Shiva Ayyadurai, an MIT trained Systems Biologist who graduated from the Department of Biological Engineering (formerly known as the Department of Food and Nutrition Science) is the Founder of the Center for Integrative Systems that performs fundamental research in systems thinking and is the home of Innovation Corps and C.L.E.A.N./R.A.W. certifications. Dr. Shiva Ayyadurai is also recognized as the Inventor of Email and holds 4 degrees from MIT. He is a Fulbright Scholar and has started 7 successful hi-tech companies including EchoMail, CytoSolve and Systems Health. He is now a candidate for US Senate from Massachusetts, running as an Independent.

International Center for Integrative Systems

The International Center for Integrative Systems is dedicated to research, education and outreach programs which help the world understand the power of systems thinking in the area of innovation, communication, science and other fields of endeavor.

Featured Research Program

Featured Research Program

Featured Standards Program

Featured Standards Program

Featured Community Program

Featured Community Program

Featured Educational Program

Featured Educational Program


The Center’s activities include:

  • Scientific Research
  • Lectures and Open Forums
  • Education Initiatives
  • Standards Development
  • Systems Visualization
  • Research Publications

Featured Publication I

Featured Publication II


The main research goal at the International Center for Integrative Systems is to explore & develop new methodologies in the areas of Media & Telecommunication Infrastructure, Arts, Art Forms & Culture, Healthcare, Transportation Systems and Innovation & Governance Systems.

The International Center for Integrative Systems believes in a shared set of resources that our community of researchers can use to advance research quicker rather than each researcher competing and reinventing resources for themselves. To this end, we have created and developed resources that are necessary for any researcher to advance their scientific work.

Systems Biology Group


Media Biomimetics

Innovation Systems Research

Food Research


PublicationsA breakthrough paper that conclusively validates the scientific foundation of Ayurveda and Siddha, based on modern control systems engineering, has been published in the International Journal of Systems of Systems Engineering (IJSSE), an eminent peer-reviewed international systems engineering journal. The paper’s research findings were presented at Sages & Scientists Conference in Carlsbad, California USA.

The paper entitled The Control Systems Engineering Foundation of Traditional Indian Medicine: The Rosetta Stone for Siddha and Ayurveda, which is accessible in Open Access format from Inderscience Publisher (and available below), begins:

“This work uncovers the scientific foundation of traditional systems of Indian medicine: Siddha and Ayurveda, from core principles shared in modern control systems engineering. The discovery provides a much-needed integrative framework to develop a systems medicine that overcomes the reductionism of modern healthcare.” (Source: V.A. Shiva Ayyadurai, Title of the Journal, 2014)

Eminent systems scientists and medical researchers are hailing the paper as a fundamental and seminal contribution to the field of integrative medicine and systems science.


The Certified R.A.W.™ symbol is an assurance to consumers that a product has been verified to be Real and 100% safe and non-GMO, must be Alive, the ingredients must have a high amount of bio-available enzymes based on testing using the revolutionary CytoSolve® technology, and must be Whole and minimally processed with a high ANDI nutrient score.
The Certified C.L.E.A.N.™ symbol is an assurance that a food product is Conscious, or safe, must be Live and be minimally processed, of Ethical origin, must be Active and tested using the revolutionary CytoSolve® technology, and must be Nourishing, as determined by ANDI Score.