Gut-Brain Health Initiative
The gut-brain connection refers to the complex communication network between the gastrointestinal (GI) tract and the brain, known as the gut-brain axis. This bi-directional system links emotional and cognitive centers of the brain with intestinal functions through neural, hormonal, and immune pathways. The vagus nerve, a major nerve in the parasympathetic nervous system, plays a key role in transmitting signals between the brain and the gut.
The gut is often called the “second brain” because it contains its own network of neurons—the enteric nervous system (ENS)—which can operate independently of the central nervous system. This system regulates digestion, motility, and even the release of neurotransmitters such as serotonin, 90% of which is produced in the gut.
A healthy gut microbiome—the community of trillions of bacteria in the intestines—also influences mood, stress response, and cognitive function. Imbalances in gut bacteria (dysbiosis) have been linked to conditions like anxiety, depression, and neurodegenerative disorders.
Maintaining gut-brain health involves a diet rich in prebiotics and probiotics, regular physical activity, quality sleep, and effective stress management. Understanding and supporting this powerful axis is essential for improving both mental and digestive health, highlighting the profound connection between the gut and the mind.
Research Progress
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The Open Science Institute’s Gut-Brain Health Initiative has now progressed to the second phase — Publication.
We need your support to move forward. Our goal is to raise $2 Million to research and reveal to the scientific community, highlighting the powerful potential of natural ingredient on Gut-Brain Health . Please support this initiative.
Systems Architecture
The Systems Architecture of Gut-Brain Health is published as a Web-based tool open to public. Click below to interact with the systems architecture
Publication
A peer-reviewed publication from theGut-Brain Health Initiative will be released soon to benefit the public by revealing powerful insights into the use of Gut-Brain for treating diseased conditions—support this initiative to advance scientific discovery and deliver real solutions through herbs.
In silico Modeling
In this phase, the Gut-Brain Health Initiative will conduct in silico modeling to identify and test the efficacy of ingredients on Dysbiosis, Metabolism and anti-ulcer activity. This phase is yet to begin.
Combination Screening
Patents
The Open Science Institute® through its Gut-Brain Health initiative is moving towards getting patents for a revolutionary compounds that affects Dysbiosis, Metabolism and anti-ulcer activity.
Licensing and Manufacturing
The Gut-Brain Health Initiative plans to discover, develop, license and manufacture a Gut-Brain Health product which supports treatment of all Gut-Brain Health associated diseases. Support our mission to bring this innovation to those who need it most. Please support this Phase by donating to the Gut-Brain Health Initiative
