Eye Health Initiative
Eye health is a vital component of overall well-being, as vision plays a central role in daily functioning, independence, and quality of life. The eye is a highly specialized organ, susceptible to damage from internal and external factors that can lead to conditions such as age-related macular degeneration (AMD), diabetic retinopathy, glaucoma, and cataracts. Four primary contributors to declining eye health include oxidative stress, retinal degeneration, inflammation, and vascular dysfunction.
Oxidative stress results from an imbalance between free radicals and antioxidants in the eye, which can damage the retina and lens proteins, contributing to diseases like AMD and cataracts. Retinal degeneration involves the deterioration of photoreceptor cells, often associated with aging or genetic disorders, leading to vision loss. Inflammation plays a dual role—while it is part of the body’s immune response, chronic ocular inflammation can damage retinal tissues and accelerate disease progression. Vascular dysfunction, particularly affecting the delicate capillaries of the retina, is a key factor in diabetic retinopathy and other ischemic eye diseases.
Maintaining eye health requires a multifaceted approach, including a nutrient-rich diet (high in lutein, zeaxanthin, vitamin A, C, E, and omega-3 fatty acids), regular eye exams, blood sugar control for diabetics, protection from UV radiation, and avoiding smoking. Advances in systems biology and in silico modeling offer promising avenues for identifying molecular targets and developing personalized therapies to prevent or reverse ocular diseases. As life expectancy increases, proactive management of eye health becomes essential to preserving vision and enhancing quality of life.
Research Progress
The Open Science Institute’s Eye Health Initiative has now progressed to the First phase — Systems Architecture.
We need your support to move forward. Our goal is to raise $150,000 to research and reveal to the scientific community, highlighting the powerful potential of eye health. Please support this initiative.
Systems Architecture
The Systems Architecture of Eye Health is published as a Web-based tool open to public. Click below to interact with the systems architecture.
Publication
A peer-reviewed publication from the Eye Health Initiative will be released soon to benefit the public by revealing powerful insights into the use of compounds for treating diseased eye conditions—support this initiative to advance scientific discovery and deliver real solutions.
In silico Modeling
In this phase, the Eye Health Initiative will conduct in silico modeling to identify and test the efficacy of ingredient/compounds on eye health. This phase is yet to begin.
Combination Screening
In this phase, combination screening will be performed to identify potential ingredient/compounds that target the biological process implicated in Eye health. This phase is yet to begin.
Patents
The Open Science Institute® through its Eye Health initiative is moving towards getting patents for a revolutionary compounds that affects eye health.
Licensing and Manufacturing
The Eye Health Initiative plans to discover, develop, license and manufacture a Eye Health product which supports treatment of many diseases. Support our mission to bring this innovation to those who need it most. Please support this Phase by donating to the Eye Health.
