
Oral Health Initiative
Periodontitis is a severe gum infection that damages the soft tissue and bone supporting the teeth, potentially leading to tooth loss if untreated. It develops from untreated gingivitis, where plaque buildup triggers inflammation. As the disease progresses, deep pockets form between the teeth and gums, harboring harmful bacteria that accelerate tissue destruction. Common symptoms include swollen, bleeding gums, bad breath, and loosening of teeth. Risk factors include poor oral hygiene, smoking, diabetes, and genetic predisposition. Periodontitis is one of the leading causes of tooth loss worldwide, affecting millions. Effective management involves professional dental care, improved oral hygiene, and lifestyle changes to prevent further progression and restore gum health.

Research Progress
The Open Science Institute’s Periodontitis research project has now progressed to the Third Phase In Silico Modeling. Our goal is to raise $750,000 to contribute an amazing real solution to Periodontal disease

Systems Architecture
The Systems Architecture of Periodontitis is publised as a web based tool open to public . Clikc below to interact with the Systems Architecture

Publication
A peer-reviewed publication reslulting from the Oral Health Research Initiative was published in 2023 in the Journal of American Dental Association. Download the paper below

In silico Modeling
In this phase, the Oral Health initiative will conduct in silico modeling to identify and test the efficay of natural compounds against the Oral Healh diseases such as Periodontitis, tooth loss and dental caries

Combination Screening

Patent
The Open Science Institute® through its Oral Health Initiative is moving towards getting patents for a revolutionary molecule that effectively combats periodontal disease, contributing breakthrough real solutions to society worldwide.

Licensing and Manufacturing
The Oral Health Initiative plans to discover, develop, license and manufacture proprietary nutraceuticals to support treatment of Periodontitis. Support our mission to bring this innovation to those who need it most. Please support this Phase by donating to the Oral Health Initiative